Created by Neuro-Immune Specialist, Dr. Kendal Stewart, Pregnenolone Plus is a custom formula that provides pregnenolone and the active precursor niacinamide for ultimate delivery of pregnenolone and aid in the protection of the mitochondrial. Pregnenolone is the key precursor pro-hormone involved in maintaining sufficient steroid hormone levels in the body. It is the precursor (building block) for other hormones in the body including cortisol, DHEA, estrogen, progesterone, testosterone and aldosterone.
Without pregnenolone there can be no human steroid hormone production.
Pregnenolone is known to modulate at least two key nerve receptors systems in the brain: NMDA receptors and GABA receptors. NMDA receptors are involved in learning, memory, and alertness. GABA receptors are involved in mood stability, relaxation, sex drive and sleep.
Niacinamide or otherwise known as Vitamin B3 works with vitamin B1, riboflavin (Vitamin B2), pyridoxine (vitamin B6), pantothenic acid, and biotin to break down and convert the carbohydrates, fats, and proteins in food into energy to help support the mitochondria. The involvement of niacin, an essential B vitamin, in cellular energy production makes it important for healthy cardiovascular function, nervous system function and immune function.
Glutathione is the body's most important intracellular antioxidant. It works inside the cells. And in addition to its antioxidant properties, glutathione is a master detoxifier. It's particularly important within the organs that are responsible for cleansing our bodies, especially the liver and kidneys, but also the lungs and intestines. Glutathione is also important to the immune system.
Phenibut is a Russian Nootropic that is most commonly used for boosting mood, assisting with anxiousness and helping to promote a healthy mood and/or sleep. Very briefly, the Phenibut molecule can be thought of as a ‘key’ to unlock ‘locks’ in the brain called GABA-receptors. The body’s own ‘key’ is called GABA, and when this unlocks the GABA-receptors, our brains have a lower response to signals from the Central Nervous System. This is what creates the effects of relaxation, social ease, pain relief and drowsiness when our bodies produce GABA. This tends to happen at night or when we are really tired.
Our bodies are constantly regulating signals from the Central Nervous System using GABA molecules. Mostly, we hardly even notice the effects. However, when we take a substance like Phenibut, which is also a ‘key’ to unlock the GABA-receptor ‘locks’ we get the same effects which could be stronger.
This formula is an Optimal methylation formula with activating co-factor created by Kendal Stewart, MD to support the methylation pathway and provide adequate Folinic Acid and methyl folate (5-MTHF).
Methyl Folate Plus™ is designed to be used in conjunction with our Methylation Complete Dissolvable Tablets OR Neuro-Immune Stabilizer Topical Cream that provides the activating co-factors to deliver the additional tetrahydrofolate to support issues associated with methylation deficiencies.. Most often poor methylators will need additional methyl folate.
The addition of Niacinamide helps support the mitochondria and supports as a cofactor for the delivery of the other ingredients in Methyl Folate Plus.
The typical indications for this product include but are not limited to:
* Presence of Folate Receptor Autoantibodies
*Homozygous (2 copies) MTHFR polymorphism
*Development (ages 8-20)
*Slow recovery from major neurological injuries
*Moderate to severe autism spectrum issues
*Poor recovery from traumatic injury
Who Needs Methyl Folate Plus? from Neurobiologix on Vimeo with Dr. Kendal Stewart.
Palmitoylethanolamide (PEA) is a bio-identical fatty acid amide that Is normally synthesized by healthy tissue In the human body in response to inflammation. PEA is made by various plants and animals and is present throughout the animal kingdom. PEA can be found in many different tissuesincluding glia, neurons, retina, white blood cells, mast cells and adipocytes. Supplementing with PEA has been sclentlffcally shown to naturally assist in the reduction of inflammation and to have neuro-protective and possibly pain control effects. This natural anti-inflammatory supports the nervous system and abnormal immune responses.*
Palmitoylethanolamide (PEA) – backed by more than 300+ medical studies, has been shown to be or assist with:
Mast cells are a type of immune system cell that responds to chemical signals from tissue injury. When mast cells “degranulate,” they release a payload of inflammatory cytokines, NGF, histamines, and other molecules in the surrounding tissue. These chemicals attract white blood cells and activate their immune response against pathogens. Mast cells also activate nociceptors (pain receptors) with the chemicals they secrete. How does it work?Palmitoylethanolamide is thought to act primarily on the Peroxisome Proliferator Activated Receptor Alpha (PPAR-α), a receptor in the cell nucleus. It also has affinity for the cannabinoid-like G-coupled receptors GPR55 and GPR119, although it has no affinity for the classical cannabinoid receptors CB1 and CB2. This is why it is sometimes referred to as a non-psychoactive “indirect endocannabinoid.”
It does not block pain signals the way opioids and other analgestics do. Instead it works upstream by supporting the healthy function of glial cells and mast cells.*
L-Citrulline has been shown to support memory issues, loss of energy, muscle weakness and maintain blood sugar levels. It has been commonly used to increase energy levels.
L-Ornithine has been shown in research studies to help boost the body's immune reaction to bacteria and viral activity. There is some evidence that L-Ornithine may be beneficial for recovery from illness and improved athletic performance, particularly body composition and strength.